I've been using a combination of multiple desktops and a tiling window manager for a few years and it's worked pretty well for me, but recently I switched over to one of these gigantic ultra-wide monitors and after weeks I still haven't figured out how to adapt some of my behaviors. I catch myself opening up a bunch of no-op windows just to make everything fit like how I'm used to.
Maybe it's worth trying out stacking one for a bit.